Qifa Xie, Ph.D.

Instructor
Dr. B.Wang's Lab of Molecular Immunology
State Key Laboratory for Agrobiotechnology
College of Biological Sciences
China Agricultural University

Tel: 010-62731278

E-Mail: xieqifa@cau.edu.cn

1. Enhancing the efficacy of DNA vaccine by targeting the dendritic cell (DC), a professional APC, via ligand-receptor fusion.

2. Quantifying the expression of Toll like receptors (TLR), adaptor protein of TLR signal pathway and cell surface marker of immune cells in mice after intramuscular injection of DNA vaccine with the adjuvants.

July, 2003, Ph. D. , College of animal science and technology, China Agricultural University, Beijing, PR. China

July 2000, M.S. , College of veterinary medicine, China Agricultural University , Beijing , P. R. China

July 1995, B.S. , College of veterinary medicine, Anhui Agricultural University , Anhui Province, PR. China

2003 - present Instructor, the State Key Laboratory for Agribiotechnology & College of Biological Sciences, China Agricultural University

1995 - 2000 Assistant researcher, Institute of Animal Husbandry and Veterinary, Anhui agriculture Academy of Science, Heifei Province

• H.L. Jin , Chong Xiao, Ze Chen, Youmin Kang, Yijie Ma, Kaichun Zhu, Qifa Xie, Yixian Tu, Yang Yu, Bin Wang. Induction of Th1 type response by DNA vaccinations with N, M, and E genes against SARS-CoV in mice. Biochemical and Biophysical Research Communications. 328 (2005) 979–986. [PDF DOWNLOAD]

•  Zhang Xiaofei, Su Genyuan, Xie Qifa , Fan Yunong 1997. Isolation and identification of AQ strain of egg drop syndrome. Journal of Anhui Agricultural, 97-98. (In Chinese)

•  Zhang Xiaofei, Xie Qifa , Pan Xiaocheng, Zhao Ruihong 2000. Culture of the attenuated A66 strain of duck hepatitis virus in chicken embryo fibroblast, Chinese Journal of Vetrinary Science, 20: 19 -21. (In Chinese).

•  Xie Qifa , Deng Zepei, Sun Binggui 2002. Localization of NOS in uterus and variation of NO Levels in serum during reproductive stage of mice. ACTA ANATOMICA SINICA, 33; 190-193. (In Chinese)

•  Xie Qifa , Deng Zepei, Sun Binggui. 2002. Research on the role of NO in the embryo resorption in mice. Chinese Journal of Veterinary Science, 22: 90-93 (In Chinese).

•  Xie Qiefa , Wu Changxin, Meng Qingyong, Li Ning 2003. The efficacy of enhanced growth by ectopic expression ghrelin and its variants using injectable myogenic vectors. Asian- Aust J Anim Sci, 17:146-152.

•  Xie Qiefa , Wu Changxin, Meng Qingyong, Li Ning. 2004. Ghrelin and truncated ghrelin variant plasmid vectors administration into skeletal muscle augments long-term growth in rats. Domestic Animal Endocrinology, 27:155-164.

•  Qifa Xie , Xiaolin Sun, Yijie Ma, Kaichun Zhu, Zhihui Ren, Huilin Jin, Bin Wang. Effects of levamisole as an adjuvant for DNA vaccination on innate immunity. (2004, in preparation).

• Huali Jin, Youming Kang, Qifa Xie, Chong Xiao, Junwu Ma, Qingge Xie, Cheng He, Xinyu Zhang, Minyong Chen, Zhansheng Yang, Zhi Sun, Fuchun Zhang, and Bin Wang. DNA prime followed by protein boost enhances neutralization and Th1 type immunity against FMDV. Virol. Immun. in press 2005.

• Huali Jin, Youmin Kang, Guoxing Zheng, Qifa Xie, Chong Xiao, Xinyu Zhang, Yang Yu, Kaichun Zhu, Gan Zhao, Fuchun Zhang, Aoshuang Chen and Bin Wang. Induction of active immune suppression by co-immunization with DNA- and protein-based vaccines. Virol, 2005 Jun 20;337(1):183-191.

• Youmin Kang, Huali Jin, Qifa Xie, Jiangmei Yin, Yang Yu, Chong Xiao, Xiaoying Zhang and Bin Wang. Effect of Levamisole as an Adjuvant on Inactivated Viral Vaccine. Vaccine, 2005 submitted.